Conformational Change and Epimerization of Diketopiperazines Containing Proline Residue in Water
نویسندگان
چکیده
منابع مشابه
A benzotriazole-mediated route to protected marine-derived hetero-2,5-diketopiperazines containing proline.
A procedure for the cyclization of dipeptidoyl benzotriazolides containing proline derivatives promoted by triethylamine under MW activation is introduced. The reaction is general for a variety of dipeptidoyl benzotriazolides and represents a very practical and convenient method for the preparation of Pro- or Hyp-derived 2,5-diketopiperazines (2,5-DKPs) and bis-DKPs with a disulfide linker. Thi...
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ژورنال
عنوان ژورنال: CHEMICAL & PHARMACEUTICAL BULLETIN
سال: 2017
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.c17-00164